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EMRE is essential for mitochondrial calcium uniporter activity in a mouse model

The mitochondrial calcium uniporter is widely accepted as the primary route of rapid calcium entry into mitochondria, where increases in matrix calcium contribute to bioenergetics but also mitochondrial permeability and cell death. Hence, regulation of uniporter activity is critical to mitochondrial...

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Détails bibliographiques
Publié dans:JCI Insight
Auteurs principaux: Liu, Julia C., Syder, Nicole C., Ghorashi, Nima S., Willingham, Thomas B., Parks, Randi J., Sun, Junhui, Fergusson, Maria M., Liu, Jie, Holmström, Kira M., Menazza, Sara, Springer, Danielle A., Liu, Chengyu, Glancy, Brian, Finkel, Toren, Murphy, Elizabeth
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7101141/
https://ncbi.nlm.nih.gov/pubmed/32017711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.134063
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