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Cyclophilin D-mediated regulation of the permeability transition pore is altered in mice lacking the mitochondrial calcium uniporter
AIMS: Knockout (KO) of the mitochondrial Ca(2+) uniporter (MCU) in mice abrogates mitochondrial Ca(2+) uptake and permeability transition pore (PTP) opening. However, hearts from global MCU-KO mice are not protected from ischaemic injury. We aimed to investigate whether adaptive alterations occur in...
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| Veröffentlicht in: | Cardiovasc Res |
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| Hauptverfasser: | , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6657279/ https://ncbi.nlm.nih.gov/pubmed/30165576 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvy218 |
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