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Attenuation of Viruses by Large-Scale Recoding of their Genomes: the Selection Is Always Biased

PURPOSE OF REVIEW: This review summarizes the current understanding of virus attenuation by large-scale recoding of viral genomes and discusses what would ultimately be necessary for construction of better and safer live modified virus vaccines. RECENT FINDINGS: It has been shown that codon and codo...

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Detaylı Bibliyografya
Yayımlandı:Curr Clin Microbiol Rep
Asıl Yazarlar: Osterrieder, Nikolaus, Kunec, Dusan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Springer International Publishing 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7100164/
https://ncbi.nlm.nih.gov/pubmed/32226716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40588-018-0080-3
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