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The expression level of class III phosphatidylinositol-3 kinase controls the degree of compensatory nephron hypertrophy

Excessive compensatory nephron hypertrophy (CNH) has been implicated in setting the stage for progressive nephron damage. Lack of a class III phosphatidylinositol 3-kinase (Pik3c3) inhibitor suitable for using in animals and lack of a Pik3c3-deficient animal model preclude the possibility of conclus...

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Détails bibliographiques
Publié dans:Am J Physiol Renal Physiol
Auteurs principaux: Liu, Ting, Dai, Caihong, Xu, Jinxian, Li, Shude, Chen, Jian-Kang
Format: Artigo
Langue:Inglês
Publié: American Physiological Society 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7099500/
https://ncbi.nlm.nih.gov/pubmed/31904289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00381.2019
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