Phosphorylation of ribosomal protein S6 mediates compensatory renal hypertrophy

The molecular mechanism underlying renal hypertrophy and progressive nephron damage remains poorly understood. Here we generated congenic ribosomal protein S6 (rpS6) knockin mice expressing non-phosphorylatable rpS6 and found that uninephrectomy-induced renal hypertrophy was significantly blunted in...

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Publicado en:Kidney Int
Autores principales: Xu, Jinxian, Chen, Jianchun, Dong, Zheng, Meyuhas, Oded, Chen, Jian-Kang
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4344886/
https://ncbi.nlm.nih.gov/pubmed/25229342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2014.302
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