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Phosphorylation of ribosomal protein S6 mediates compensatory renal hypertrophy

The molecular mechanism underlying renal hypertrophy and progressive nephron damage remains poorly understood. Here we generated congenic ribosomal protein S6 (rpS6) knockin mice expressing non-phosphorylatable rpS6 and found that uninephrectomy-induced renal hypertrophy was significantly blunted in...

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Detalhes bibliográficos
Publicado no:Kidney Int
Main Authors: Xu, Jinxian, Chen, Jianchun, Dong, Zheng, Meyuhas, Oded, Chen, Jian-Kang
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4344886/
https://ncbi.nlm.nih.gov/pubmed/25229342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2014.302
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