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Phosphorylation of Ribosomal Protein S6 Mediates Mammalian Target of Rapamycin Complex 1–Induced Parathyroid Cell Proliferation in Secondary Hyperparathyroidism

Secondary hyperparathyroidism is characterized by increased serum parathyroid hormone (PTH) level and parathyroid cell proliferation. However, the molecular pathways mediating the increased parathyroid cell proliferation remain undefined. Here, we found that the mTOR pathway was activated in the par...

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Détails bibliographiques
Publié dans:J Am Soc Nephrol
Auteurs principaux: Volovelsky, Oded, Cohen, Gili, Kenig, Ariel, Wasserman, Gilad, Dreazen, Avigail, Meyuhas, Oded, Silver, Justin, Naveh-Many, Tally
Format: Artigo
Langue:Inglês
Publié: American Society of Nephrology 2016
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4814192/
https://ncbi.nlm.nih.gov/pubmed/26283674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2015040339
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