MitoQ regulates redox-related noncoding RNAs to preserve mitochondrial network integrity in pressure-overload heart failure

Evidence suggests that mitochondrial network integrity is impaired in cardiomyocytes from failing hearts. While oxidative stress has been implicated in heart failure (HF)-associated mitochondrial remodeling, the effect of mitochondrial-targeted antioxidants, such as mitoquinone (MitoQ), on the mitoc...

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Vydáno v:Am J Physiol Heart Circ Physiol
Hlavní autoři: Kim, Seulhee, Song, Jiajia, Ernst, Patrick, Latimer, Mary N., Ha, Chae-Myeong, Goh, Kah Yong, Ma, Wenxia, Rajasekaran, Namakkal-Soorappan, Zhang, Jianhua, Liu, Xiaoguang, Prabhu, Sumanth D., Qin, Gangjian, Wende, Adam R., Young, Martin E., Zhou, Lufang
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2020
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7099446/
https://ncbi.nlm.nih.gov/pubmed/32004065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00617.2019
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