MitoQ regulates redox-related noncoding RNAs to preserve mitochondrial network integrity in pressure-overload heart failure

Evidence suggests that mitochondrial network integrity is impaired in cardiomyocytes from failing hearts. While oxidative stress has been implicated in heart failure (HF)-associated mitochondrial remodeling, the effect of mitochondrial-targeted antioxidants, such as mitoquinone (MitoQ), on the mitoc...

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Pubblicato in:Am J Physiol Heart Circ Physiol
Autori principali: Kim, Seulhee, Song, Jiajia, Ernst, Patrick, Latimer, Mary N., Ha, Chae-Myeong, Goh, Kah Yong, Ma, Wenxia, Rajasekaran, Namakkal-Soorappan, Zhang, Jianhua, Liu, Xiaoguang, Prabhu, Sumanth D., Qin, Gangjian, Wende, Adam R., Young, Martin E., Zhou, Lufang
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2020
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7099446/
https://ncbi.nlm.nih.gov/pubmed/32004065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00617.2019
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