Mitoquinone ameliorates pressure overload-induced cardiac fibrosis and left ventricular dysfunction in mice

Increasing evidence indicates that mitochondrial-associated redox signaling contributes to the pathophysiology of heart failure (HF). The mitochondrial-targeted antioxidant, mitoquinone (MitoQ), is capable of modifying mitochondrial signaling and has shown beneficial effects on HF-dependent mitochon...

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Goh, Kah Yong, He, Li, Song, Jiajia, Jinno, Miki, Rogers, Aaron J., Sethu, Palaniappan, Halade, Ganesh V., Rajasekaran, Namakkal Soorappan, Liu, Xiaoguang, Prabhu, Sumanth D., Darley-Usmar, Victor, Wende, Adam R., Zhou, Lufang
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6330374/
https://ncbi.nlm.nih.gov/pubmed/30641298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2019.101100
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