Arginine metabolic control of airway inflammation

Inducible nitric oxide synthase (iNOS) and arginase-2 (ARG2) share a common substrate, arginine. Higher expression of iNOS and exhaled NO are linked to airway inflammation in patients. iNOS deletion in animal models suggests that eosinophilic inflammation is regulated by arginine metabolism. Moreove...

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Dades bibliogràfiques
Publicat a:JCI Insight
Autors principals: Asosingh, Kewal, Lauruschkat, Chris D., Alemagno, Mario, Frimel, Matthew, Wanner, Nicholas, Weiss, Kelly, Kessler, Sean, Meyers, Deborah A., Bennett, Carole, Xu, Weiling, Erzurum, Serpil
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2020
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7098726/
https://ncbi.nlm.nih.gov/pubmed/31996482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.127801
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