Arginine metabolic control of airway inflammation

Inducible nitric oxide synthase (iNOS) and arginase-2 (ARG2) share a common substrate, arginine. Higher expression of iNOS and exhaled NO are linked to airway inflammation in patients. iNOS deletion in animal models suggests that eosinophilic inflammation is regulated by arginine metabolism. Moreove...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:JCI Insight
Egile Nagusiak: Asosingh, Kewal, Lauruschkat, Chris D., Alemagno, Mario, Frimel, Matthew, Wanner, Nicholas, Weiss, Kelly, Kessler, Sean, Meyers, Deborah A., Bennett, Carole, Xu, Weiling, Erzurum, Serpil
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Clinical Investigation 2020
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7098726/
https://ncbi.nlm.nih.gov/pubmed/31996482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.127801
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