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Kaempferol ameliorates Cisplatin induced nephrotoxicity by modulating oxidative stress, inflammation and apoptosis via ERK and NF-κB pathways

Anticancer drug like Cisplatin are associated with serious problem like nephrotoxicity. The effect of Kaempferol is a plant-derived flavonoid compound. The present work evaluated the effect of Kaempferol in mouse model of Cisplatin mediated nephrotoxicity also the involved mechanism. Oxidative stres...

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Bibliographische Detailangaben
Veröffentlicht in:AMB Express
Hauptverfasser: Wang, Zhu, Sun, Wansen, Sun, Xi, Wang, Ye, Zhou, Meilan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer Berlin Heidelberg 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7098399/
https://ncbi.nlm.nih.gov/pubmed/32219583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13568-020-00993-w
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