Common Genetic Variants in the Complement System and their Potential Link with Disease Susceptibility and Outcome of Invasive Bacterial Infection

Streptococcus pneumoniae and Neisseria meningitidis are pathogens that frequently colonize the nasopharynx in an asymptomatic manner but are also a cause of invasive bacterial infections mainly in young children. The complement system plays a crucial role in humoral immunity, complementing the abili...

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Vydáno v:J Innate Immun
Hlavní autoři: van den Broek, Bryan, van der Flier, Michiel, de Groot, Ronald, de Jonge, Marien I., Langereis, Jeroen D.
Médium: Artigo
Jazyk:Inglês
Vydáno: S. Karger AG 2020
Témata:
Review Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7098274/
https://ncbi.nlm.nih.gov/pubmed/31269507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000500545
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