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Complement factor D haplodeficiency is associated with a reduced complement activation speed and diminished bacterial killing
OBJECTIVES: Complete deficiency of alternative pathway (AP) complement factors, explained by homozygous mutations, is a well‐known risk factor for invasive bacterial infections; however, this is less obvious for heterozygous mutations. We describe two siblings with a heterozygous NM_001928.3(CFD):c....
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| Udgivet i: | Clin Transl Immunology |
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| Main Authors: | , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
John Wiley and Sons Inc.
2021
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8019133/ https://ncbi.nlm.nih.gov/pubmed/33841879 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cti2.1256 |
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