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RESTORATION OF F508-DEL FUNCTION BY TRANSCOMPLEMENTATION: THE PARTNERS MEET IN THE ENDOPLASMIC RETICULUM
BACKGROUND/AIMS: Because of the small size of adeno-associated virus, AAV, the cystic fibrosis conductance regulator, CFTR, cDNA is too large to fit within AAV and must be truncated. We report here on two truncated versions of CFTR, which, when inserted into AAV1 and used to infect airway cells, res...
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| Udgivet i: | Cell Physiol Biochem |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7097968/ https://ncbi.nlm.nih.gov/pubmed/31026390 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.33594/000000089 |
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