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F2r negatively regulates osteoclastogenesis through inhibiting the Akt and NFκB signaling pathways
G-protein-coupled receptors (GPCRs) are pivotal drug targets for many diseases. Coagulation Factor II Thrombin Receptor (F2R) is an important member of GPCR family that is highly expressed in osteoclasts. However, the role of F2r in osteoclasts is still unclear. Here, to examine the functions of F2r...
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| Publicado no: | Int J Biol Sci |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Ivyspring International Publisher
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7097923/ https://ncbi.nlm.nih.gov/pubmed/32226307 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.41867 |
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