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PTPσ Knockdown in Lampreys Impairs Reticulospinal Axon Regeneration and Neuronal Survival After Spinal Cord Injury

Traumatic spinal cord injury (SCI) results in persistent functional deficits due to the lack of axon regeneration within the mammalian CNS. After SCI, chondroitin sulfate proteoglycans (CSPGs) inhibit axon regrowth via putative interactions with the LAR-family protein tyrosine phosphatases, PTPσ and...

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Bibliografiske detaljer
Udgivet i:Front Cell Neurosci
Main Authors: Rodemer, William, Zhang, Guixin, Sinitsa, Isabelle, Hu, Jianli, Jin, Li-qing, Li, Shuxin, Selzer, Michael E.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7096546/
https://ncbi.nlm.nih.gov/pubmed/32265663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2020.00061
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