PTPσ Knockdown in Lampreys Impairs Reticulospinal Axon Regeneration and Neuronal Survival After Spinal Cord Injury

Traumatic spinal cord injury (SCI) results in persistent functional deficits due to the lack of axon regeneration within the mammalian CNS. After SCI, chondroitin sulfate proteoglycans (CSPGs) inhibit axon regrowth via putative interactions with the LAR-family protein tyrosine phosphatases, PTPσ and...

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Detalhes bibliográficos
Publicado no:Front Cell Neurosci
Main Authors: Rodemer, William, Zhang, Guixin, Sinitsa, Isabelle, Hu, Jianli, Jin, Li-qing, Li, Shuxin, Selzer, Michael E.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Cellular Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7096546/
https://ncbi.nlm.nih.gov/pubmed/32265663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2020.00061
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