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MicroRNAs Cause Accelerated Decay of Short-Tailed Target mRNAs
MicroRNAs (miRNAs) specify the recruitment of deadenylases to mRNA targets. Despite this recruitment, we find that miRNAs have almost no effect on steady-state poly(A)-tail lengths of their targets in mouse fibroblasts, which motivates the acquisition of pre-steady-state measurements of the effects...
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| Udgivet i: | Mol Cell |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7096130/ https://ncbi.nlm.nih.gov/pubmed/31902668 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2019.12.004 |
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