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ABIRATERONE ACETATE TREATMENT LOWERS 11-OXYGENATED ANDROGENS
CONTEXT: The human adrenal is the dominant source of androgens in castration-resistant prostate cancer (CRPC) and classic 21-hydroxylase deficiency (21OHD). Abiraterone, derived from the prodrug abiraterone acetate (AA), inhibits the activity of cytochrome P450 17-hydroxylase/17,20-lyase (CYP17A1),...
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| Publicat a: | Eur J Endocrinol |
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| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7096060/ https://ncbi.nlm.nih.gov/pubmed/32045360 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/EJE-19-0905 |
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