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gp41: HIV's shy protein

The first X-ray crystal structures of gp41, the protein that mediates fusion of HIV-1 to target cells, were solved in the mid-1990s. The structures provide a foundation for understanding viral entry and the mechanism of action of compounds that block fusion. The first fusion inhibitor has recently e...

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Detalhes bibliográficos
Publicado no:Nat Med
Main Authors: Zwick, Michael B, Saphire, Erica O, Burton, Dennis R
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group US 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7095992/
https://ncbi.nlm.nih.gov/pubmed/14760422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm0204-133
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