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Bioactivation of leukotoxins to their toxic diols by epoxide hydrolase

Leukotoxin is a linoleic acic oxide produced by leukocytes and has been associated with the multiple organ failure and adult respiratory distress syndrome seen in some severe burn patients. Leukotoxin has been reported to be toxic when injected into animals intravenously. Herein, we report that this...

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Vydáno v:Nat Med
Hlavní autoři: Moghaddam, Mehran F., Grant, David F., Cheek, Jeffrey M., Greene, Jessica F., Williamson, Kristin C., Hammock, Bruce D.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group US 1997
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7095900/
https://ncbi.nlm.nih.gov/pubmed/9142128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm0597-562
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