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Bioactivation of leukotoxins to their toxic diols by epoxide hydrolase

Leukotoxin is a linoleic acic oxide produced by leukocytes and has been associated with the multiple organ failure and adult respiratory distress syndrome seen in some severe burn patients. Leukotoxin has been reported to be toxic when injected into animals intravenously. Herein, we report that this...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Nat Med
Päätekijät: Moghaddam, Mehran F., Grant, David F., Cheek, Jeffrey M., Greene, Jessica F., Williamson, Kristin C., Hammock, Bruce D.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group US 1997
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7095900/
https://ncbi.nlm.nih.gov/pubmed/9142128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm0597-562
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