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Bioactivation of leukotoxins to their toxic diols by epoxide hydrolase

Leukotoxin is a linoleic acic oxide produced by leukocytes and has been associated with the multiple organ failure and adult respiratory distress syndrome seen in some severe burn patients. Leukotoxin has been reported to be toxic when injected into animals intravenously. Herein, we report that this...

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Bibliografski detalji
Izdano u:Nat Med
Glavni autori: Moghaddam, Mehran F., Grant, David F., Cheek, Jeffrey M., Greene, Jessica F., Williamson, Kristin C., Hammock, Bruce D.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group US 1997
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7095900/
https://ncbi.nlm.nih.gov/pubmed/9142128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm0597-562
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