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A RhoA-derived peptide inhibits syncytium formation induced by respiratory syncytial virus and parainfluenza virus type 3

The fusion glycoproteins of human respiratory syncytial virus (RSV) and human parainfluenza virus type-3 (PIV-3) mediate virus entry and syncytium formation. Interaction between the fusion protein of RSV and RhoA, a small GTPase, facilitates virus-induced syncytium formation. We show here a RhoA-der...

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Publicat a:Nat Med
Autors principals: Pastey, Manoj K., Gower, Tara L., Spearman, Paul W., Crowe, James E., Graham, Barney S.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group US 2000
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7095870/
https://ncbi.nlm.nih.gov/pubmed/10613821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/71503
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