RhoA Signaling Is Required for Respiratory Syncytial Virus-Induced Syncytium Formation and Filamentous Virion Morphology

Respiratory syncytial virus (RSV) is an important human pathogen that can cause severe and life-threatening respiratory infections in infants, the elderly, and immunocompromised adults. RSV infection of HEp-2 cells induces the activation of RhoA, a small GTPase. We therefore asked whether RhoA signa...

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Главные авторы: Gower, Tara L., Pastey, Manoj K., Peeples, Mark E., Collins, Peter L., McCurdy, Lewis H., Hart, Timothy K., Guth, Alex, Johnson, Teresa R., Graham, Barney S.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2005
Предметы:
Structure and Assembly
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1082718/
https://ncbi.nlm.nih.gov/pubmed/15827147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.9.5326-5336.2005
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