Antiviral Activity of RhoA-Derived Peptides against Respiratory Syncytial Virus Is Dependent on Formation of Peptide Dimers

A synthetic peptide containing amino acids 77 to 95 of the intracellular GTPase RhoA has previously been shown to inhibit replication of respiratory syncytial virus (RSV) in cultured cells. We show that residues 80 to 90 of RhoA are sufficient for this activity and that the cysteine residue at posit...

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Bibliographic Details
Main Authors: Budge, Philip J., Lebowitz, Jacob, Graham, Barney S.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2003
Subjects:
Antiviral Agents
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC253766/
https://ncbi.nlm.nih.gov/pubmed/14576104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.11.3470-3477.2003
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