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Orthotopic Patient-Derived Pancreatic Cancer Xenografts Engraft Into the Pancreatic Parenchyma, Metastasize and Induce Muscle Wasting to Recapitulate the Human Disease
OBJECTIVE: Limitations associated with current animal models serve as a major obstacle to reliable preclinical evaluation of therapies in pancreatic cancer (PC). In an effort to develop more reliable preclinical models, we have recently established a subcutaneous patient-derived xenograft (PDX) mode...
Gardado en:
| Publicado en: | Pancreas |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7094873/ https://ncbi.nlm.nih.gov/pubmed/28609371 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MPA.0000000000000843 |
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