The receptor tyrosine kinase AXL mediates nuclear translocation of the epidermal growth factor receptor

The epidermal growth factor receptor (EGFR) is a therapeutic target in patients with various cancers. Unfortunately, resistance to EGFR-targeted therapeutics is common. Previous studies identified two mechanisms of resistance to the EGFR monoclonal antibody cetuximab: Nuclear translocation of EGFR b...

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Detaylı Bibliyografya
Yayımlandı:Sci Signal
Asıl Yazarlar: Brand, Toni M., Iida, Mari, Corrigan, Kelsey L., Braverman, Cara M., Coan, John P., Flanigan, Bailey G., Stein, Andrew P., Salgia, Ravi, Rolff, Jana, Kimple, Randall J., Wheeler, Deric L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2017
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7094775/
https://ncbi.nlm.nih.gov/pubmed/28049763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aag1064
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