Membrane topology of gp41 and amyloid precursor protein: Interfering transmembrane interactions as potential targets for HIV and Alzheimer treatment

The amyloid precursor protein (APP), that plays a critical role in the development of senile plaques in Alzheimer disease (AD), and the gp41 envelope protein of the human immunodeficiency virus (HIV), the causative agent of the acquired immunodeficiency syndrome (AIDS), are single-spanning type-1 tr...

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Vydáno v:Biochim Biophys Acta Biomembr
Hlavní autoři: Abad, Concepción, Martínez-Gil, Luis, Tamborero, Silvia, Mingarro, Ismael
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier B.V. 2009
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7094694/
https://ncbi.nlm.nih.gov/pubmed/19619504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2009.07.008
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