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Structural Plasticity in the Topology of the Membrane-Interacting Domain of HIV-1 gp41

We use a number of computational and experimental approaches to investigate the membrane topology of the membrane-interacting C-terminal domain of the HIV-1 gp41 fusion protein. Several putative transmembrane regions are identified using hydrophobicity analysis based on the Wimley-White scales, incl...

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Detalhes bibliográficos
Main Authors: Kyrychenko, Alexander, Freites, J. Alfredo, He, Jing, Tobias, Douglas J., Wimley, William C., Ladokhin, Alexey S.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3945775/
https://ncbi.nlm.nih.gov/pubmed/24507601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.12.032
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