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Validation of Depth-Dependent Fluorescence Quenching in Membranes by Molecular Dynamics Simulation of Tryptophan Octyl Ester in POPC Bilayer

Depth-dependent fluorescence quenching is an important tool for studying the penetration of proteins and peptides into lipid bilayers. Extracting quantitative information from quenching data is, however, complicated by (1) a limited number of experimentally available quenchers and (2) by thermal dis...

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Bibliographic Details
Main Authors: Kyrychenko, Alexander, Tobias, Douglas J., Ladokhin, Alexey S.
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3652981/
https://ncbi.nlm.nih.gov/pubmed/23528135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp310638f
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