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Membrane topology of gp41 and amyloid precursor protein: Interfering transmembrane interactions as potential targets for HIV and Alzheimer treatment

The amyloid precursor protein (APP), that plays a critical role in the development of senile plaques in Alzheimer disease (AD), and the gp41 envelope protein of the human immunodeficiency virus (HIV), the causative agent of the acquired immunodeficiency syndrome (AIDS), are single-spanning type-1 tr...

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Bibliografiska uppgifter
I publikationen:Biochim Biophys Acta Biomembr
Huvudupphovsmän: Abad, Concepción, Martínez-Gil, Luis, Tamborero, Silvia, Mingarro, Ismael
Materialtyp: Artigo
Språk:Inglês
Publicerad: Elsevier B.V. 2009
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7094694/
https://ncbi.nlm.nih.gov/pubmed/19619504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2009.07.008
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