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Negative regulation of TBK1‐mediated antiviral immunity
TANK‐binding kinase 1 (TBK1) plays pivotal roles in antiviral innate immunity. TBK1 mediates the activation of interferon regulatory factor (IRF) 3, leading to the induction of type I IFNs (IFN‐α/β) following viral infections. TBK1 must be tightly regulated to effectively control viral infections an...
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| Publicado no: | FEBS Lett |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7094513/ https://ncbi.nlm.nih.gov/pubmed/23395611 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2013.01.052 |
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