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Correlation between dissociation and catalysis of SARS-CoV main protease
The dimeric interface of severe acute respiratory syndrome coronavirus main protease is a potential target for the anti-SARS drug development. We have generated C-terminal truncated mutants by serial truncations. The quaternary structure of the enzyme was analyzed using both sedimentation velocity a...
Enregistré dans:
| Publié dans: | Arch Biochem Biophys |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Elsevier Inc.
2008
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7094404/ https://ncbi.nlm.nih.gov/pubmed/18275836 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2008.01.023 |
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