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Correlation between dissociation and catalysis of SARS-CoV main protease

The dimeric interface of severe acute respiratory syndrome coronavirus main protease is a potential target for the anti-SARS drug development. We have generated C-terminal truncated mutants by serial truncations. The quaternary structure of the enzyme was analyzed using both sedimentation velocity a...

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Detalhes bibliográficos
Publicado no:Arch Biochem Biophys
Main Authors: Lin, Pei-Ying, Chou, Chi-Yuan, Chang, Hui-Chuan, Hsu, Wen-Chi, Chang, Gu-Gang
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Inc. 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7094404/
https://ncbi.nlm.nih.gov/pubmed/18275836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2008.01.023
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