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Essential covalent linkage between the chymotrypsin-like domain and the extra domain of the SARS-CoV main protease

The main protease of the coronavirus causing severe acute respiratory syndrome performs proteolytic processing of the viral polyproteins. The active form of the enzyme is a homodimer with each subunit consisting of three structural domains. Domains I and II, hosting the complete catalytic machinery,...

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Detalles Bibliográficos
Publicado en:J Biochem
Main Authors: Tsai, Meng-Ying, Chang, Wei-Hsin, Liang, Jin-Yi, Lin, Long-Liu, Chang, Gu-Gang, Chang, Hui-Ping
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7110190/
https://ncbi.nlm.nih.gov/pubmed/20587646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jb/mvq071
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