Comparison of the efficiency of antibody selection from semi-synthetic scFv and non-immune Fab phage display libraries against protein targets for rapid development of diagnostic immunoassays

Rapid development of diagnostic immunoassays against novel emerging or genetically modified pathogens in an emergency situation is dependent on the timely isolation of specific antibodies. Non-immune antibody phage display libraries are an efficient in vitro method for selecting monoclonal antibodie...

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Publicat a:J Immunol Methods
Autors principals: Chan, Conrad E.Z., Chan, Annie H.Y., Lim, Angeline P.C., Hanson, Brendon J.
Format: Artigo
Idioma:Inglês
Publicat: Elsevier B.V. 2011
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7094349/
https://ncbi.nlm.nih.gov/pubmed/21856306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jim.2011.08.005
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