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Discovery of Hapten-Specific scFv from a Phage Display Library and Applications for HER2-Positive Tumor Imaging

[Image: see text] In this study, an anti-hapten antibody (single chain Fv, scFv) against a hapten probe was developed as a unique reporter system for molecular imaging or therapy. The hapten peptide (histamine-succinyl-GSYK, Him) was synthesized for phage displayed scFv affinity selection and for co...

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Detalhes bibliográficos
Main Authors: Kim, Hye-Yeong, Wang, Xiaolei, Wahlberg, Brendon, Edwards, W. Barry
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4103757/
https://ncbi.nlm.nih.gov/pubmed/24898150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc500173f
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