Comparison of the efficiency of antibody selection from semi-synthetic scFv and non-immune Fab phage display libraries against protein targets for rapid development of diagnostic immunoassays

Rapid development of diagnostic immunoassays against novel emerging or genetically modified pathogens in an emergency situation is dependent on the timely isolation of specific antibodies. Non-immune antibody phage display libraries are an efficient in vitro method for selecting monoclonal antibodie...

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Pubblicato in:J Immunol Methods
Autori principali: Chan, Conrad E.Z., Chan, Annie H.Y., Lim, Angeline P.C., Hanson, Brendon J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier B.V. 2011
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7094349/
https://ncbi.nlm.nih.gov/pubmed/21856306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jim.2011.08.005
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