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Molecular modeling and chemical modification for finding peptide inhibitor against severe acute respiratory syndrome coronavirus main proteinase
Severe acute respiratory syndrome (SARS) is a respiratory disease caused by a newly found virus, called SARS coronavirus. In this study, the cleavage mechanism of the SARS coronavirus main proteinase (M(pro) or 3CL(pro)) on the octapeptide NH(2)-AVLQ ↓ SGFR-COOH was investigated using molecular mech...
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| Publicado no: | Anal Biochem |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier Inc.
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7094278/ https://ncbi.nlm.nih.gov/pubmed/15691506 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2004.10.003 |
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