Regulatory T cells promote alloengraftment in a model of late-gestation in utero hematopoietic cell transplantation

In utero hematopoietic cell transplantation (IUHCT) has the potential to cure congenital hematologic disorders including sickle cell disease. However, the window of opportunity for IUHCT closes with the acquisition of T-cell immunity, beginning at approximately 14 weeks gestation, posing significant...

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Bibliographic Details
Published in:Blood Adv
Main Authors: Riley, John S., McClain, Lauren E., Stratigis, John D., Coons, Barbara E., Ahn, Nicholas J., Li, Haiying, Loukogeorgakis, Stavros P., Fachin, Camila G., Dias, Andre I. B. S., Flake, Alan W., Peranteau, William H.
Format: Artigo
Language:Inglês
Published: American Society of Hematology 2020
Subjects:
Transplantation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7094012/
https://ncbi.nlm.nih.gov/pubmed/32203584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2019001208
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