Pre-existing Maternal Antibodies Cause Rapid Prenatal Rejection of Allotransplants in the Mouse Model of In Utero Hematopoietic Cell Transplantation

In utero hematopoietic cell transplantation (IUHCT) is a nonmyeloablative nonimmunosuppressive alternative to postnatal hematopoietic stem cell transplantation (HSCT) for the treatment of congenital hemoglobinopathies. Anti-HLA donor-specific antibodies (DSA) are associated with a high incidence of...

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Publicat a:J Immunol
Autors principals: Riley, John S., McClain, Lauren E., Stratigis, John D., Coons, Barbara E., Li, Haiying, Hartman, Heather A., Peranteau, William H.
Format: Artigo
Idioma:Inglês
Publicat: 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6103848/
https://ncbi.nlm.nih.gov/pubmed/30021770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1800183
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