Regulatory T cells promote alloengraftment in a model of late-gestation in utero hematopoietic cell transplantation

In utero hematopoietic cell transplantation (IUHCT) has the potential to cure congenital hematologic disorders including sickle cell disease. However, the window of opportunity for IUHCT closes with the acquisition of T-cell immunity, beginning at approximately 14 weeks gestation, posing significant...

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Detalhes bibliográficos
Publicado no:Blood Adv
Main Authors: Riley, John S., McClain, Lauren E., Stratigis, John D., Coons, Barbara E., Ahn, Nicholas J., Li, Haiying, Loukogeorgakis, Stavros P., Fachin, Camila G., Dias, Andre I. B. S., Flake, Alan W., Peranteau, William H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2020
Assuntos:
Transplantation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7094012/
https://ncbi.nlm.nih.gov/pubmed/32203584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2019001208
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