PRKAR1A deficiency impedes hypertrophy and reduces heart size

Protein kinase A (PKA) activity is pivotal for proper functioning of the human heart, and its dysregulation has been implicated in a variety of cardiac pathologies. PKA regulatory subunit 1α (R1α, encoded by the PRKAR1A gene) is highly expressed in the heart, and controls PKA kinase activity by sequ...

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Bibliografiske detaljer
Udgivet i:Physiol Rep
Main Authors: Liu, Yuening, Xia, Peng, Chen, Jingrui, Bandettini, W. Patricia, Kirschner, Lawrence S., Stratakis, Constantine A., Cheng, Zhaokang
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2020
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7093752/
https://ncbi.nlm.nih.gov/pubmed/32212257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.14405
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