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PRKAR1A deficiency impedes hypertrophy and reduces heart size
Protein kinase A (PKA) activity is pivotal for proper functioning of the human heart, and its dysregulation has been implicated in a variety of cardiac pathologies. PKA regulatory subunit 1α (R1α, encoded by the PRKAR1A gene) is highly expressed in the heart, and controls PKA kinase activity by sequ...
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| Опубликовано в: : | Physiol Rep |
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| Главные авторы: | , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
John Wiley and Sons Inc.
2020
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7093752/ https://ncbi.nlm.nih.gov/pubmed/32212257 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.14405 |
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