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Metabolic mapping of glioblastoma stem cells reveals NADH fluxes associated with glioblastoma phenotype and survival

Significance: Glioblastoma multiforme (GBM) is the most frequently diagnosed adult primary brain malignancy with poor patient prognosis. GBM can recur despite aggressive treatment due to therapeutically resistant glioblastoma stem cells (GSCs) that may exhibit metabolic plasticity. Aim: Intrinsic ni...

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Detalhes bibliográficos
Publicado no:J Biomed Opt
Main Authors: Schroeder, Alexandra B., Pointer, Kelli B., Clark, Paul A., Datta, Rupsa, Kuo, John S., Eliceiri, Kevin W.
Formato: Artigo
Idioma:Inglês
Publicado em: Society of Photo-Optical Instrumentation Engineers 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7093735/
https://ncbi.nlm.nih.gov/pubmed/32216192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1117/1.JBO.25.3.036502
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