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Administration of non-torsadogenic human Ether-à-go-go Related Gene inhibitors is associated with better survival for high hERG-expressing glioblastoma patients

PURPOSE: Glioblastoma (GBM) is the most malignant primary brain tumor, with a median survival of less than two years. More effective therapeutic approaches are needed to improve clinical outcomes. EXPERIMENTAL DESIGN: Glioblastoma patient-derived cells (GPDCs) were isolated from patient GBMs and imp...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Pointer, Kelli B., Clark, Paul A., Eliceiri, Kevin W., Salamat, M. Shahriar, Robertson, Gail A., Kuo, John S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5627655/
https://ncbi.nlm.nih.gov/pubmed/27635088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-15-3169
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