Janus effect of glucocorticoids on differentiation of muscle fibro/adipogenic progenitors

Muscle resident fibro-adipogenic progenitors (FAPs), support muscle regeneration by releasing cytokines that stimulate the differentiation of myogenic stem cells. However, in non-physiological contexts (myopathies, atrophy, aging) FAPs cause fibrotic and fat infiltrations that impair muscle function...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Cerquone Perpetuini, Andrea, Giuliani, Giulio, Reggio, Alessio, Cerretani, Mauro, Santoriello, Marisabella, Stefanelli, Roberta, Palma, Alessandro, Vumbaca, Simone, Harper, Steven, Castagnoli, Luisa, Bresciani, Alberto, Cesareni, Gianni
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7093513/
https://ncbi.nlm.nih.gov/pubmed/32210313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-62194-6
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