Adipogenesis of skeletal muscle fibro/adipogenic progenitors is affected by the WNT5a/GSK3/β-catenin axis

Fibro/Adipogenic Progenitors (FAPs) are muscle-interstitial progenitors mediating pro-myogenic signals that are critical for muscle homeostasis and regeneration. In myopathies, the autocrine/paracrine constraints controlling FAP adipogenesis are released causing fat infiltrates. Here, by combining p...

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Veröffentlicht in:Cell Death Differ
Hauptverfasser: Reggio, Alessio, Rosina, Marco, Palma, Alessandro, Cerquone Perpetuini, Andrea, Petrilli, Lucia Lisa, Gargioli, Cesare, Fuoco, Claudia, Micarelli, Elisa, Giuliani, Giulio, Cerretani, Mauro, Bresciani, Alberto, Sacco, Francesca, Castagnoli, Luisa, Cesareni, Gianni
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7492278/
https://ncbi.nlm.nih.gov/pubmed/32382110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-020-0551-y
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